抗菌素大规模应用之前,肺结核自愈并非极其罕见, 营养非常重要, 所以叫“富贵病”

来源: 2019-01-18 19:30:23 [旧帖] [给我悄悄话] 本文已被阅读:

下面这篇文章有27例。

Mycobacterium tuberculosis–Specific Cellular Immune Profiles Suggest Bacillary Persistence Decades after Spontaneous Cure in Untreated Tuberculosis

Kerry A. Millington,1 Sarah Gooding,2 Timothy S. C. Hinks,3 D. John M. Reynolds,2 and Ajit Lalvani1 1 Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, 2 Oxford Radcliffe Hospitals NHS Trust, John Radcliffe Hospital, Oxford, and 3 Division of Infection, Inflammation and Immunity, Allergy and Inflammation Research, University of Southampton School of Medicine, Southampton General Hospital, Southampton, United Kingdom

Individuals with self-healed tuberculosis from the preantibiotic era offer a unique insight into the natural history of and protective immunity to tuberculosis. In 27 such persons whose tuberculosis self-healed 》50 years earlier, circulating Mycobacterium tuberculosis antigen–specific interferon g (IFN-g)– and interleukin 2 (IL-2)–secreting T cells were detected ex vivo in 16 and 19 individuals, respectively。