测算你是否需要服用他汀类药物的计算器--- Adult Treatment Panel (ATP) III calculator

来源: 2015-04-14 17:16:10 [博客] [旧帖] [给我悄悄话] 本文已被阅读:

1. 点击以下计算器链接, 输入你最近体检的胆固醇等数值,如果算出来是>7.5%,那么医生会建议你服药降胆固醇. 
我算了一下我的: Less than 1%.

Adult Treatment Panel (ATP III) - GlobalRPh

2. NEJM关于使用他汀类药物的讨论和解释的文章:

http://www.nejm.org/doi/full/10.1056/NEJMclde1314766


3. 这个链接的后半部分会指导你先从改变生活方式开始,无效后如何进行药物治疗(介绍药物种类,副作用和禁忌症等): 

ATP III Guidelines At-A-Glance Quick Desk Reference

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More Americans could benefit from statins

Cholesterol-lowering statin drugs could be prescribed to an estimated 33 million Americans without cardiovascular disease who have a 7.5 percent or higher risk for a heart attack or stroke within the next 10 years. That’s according to a new cholesterol guideline from the American Heart Association and American College of Cardiology.

This is a dramatic change from the 2002 federal cholesterol guideline, which recommended that people should only take a statin if their 10-year risk level exceeded 20 percent. The old guideline only considered a person’s risk for heart disease, leaving out the risk for stroke.

Statins are drugs that lower the amount of cholesterol circulating in the blood. Seven statin drugs are currently available in the U.S.

“We’ve been undertreating people who need statin therapy in this country,” said American Heart Association volunteer Donald Lloyd-Jones, M.D., one of 20 experts on the committee that wrote the new guideline.

Examples of groups that would exceed the 7.5 percent risk threshold and therefore benefit from statin therapy include white women over 60 who smoke and have high blood pressure and African-American men over 50 with high blood pressure.

“Statins lower cholesterol levels, but what they really target is overall cardiovascular risk,” said Lloyd-Jones, a preventive cardiologist and chair of the Department of Preventive Medicine at Northwestern University Feinberg School of Medicine in Chicago.

Ideally, the level of bad (LDL) cholesterol should be below 100 milligrams per deciliter of blood (mg/dL). It is considered high at 160 mg/dL. For someone taking a statin, the risk for a heart attack or stroke drops by about 20 percent for each 39 mg/dL reduction in bad (LDL) cholesterol, according to the guideline. Bad cholesterol is considered high at 160 mg/dL.

The guideline recommends statin therapy for the following groups:

  • People without cardiovascular disease who are 40 to 75 years old and have a 7.5 percent or higher risk for heart attack or stroke within 10 years.
  • People with a history of heart attack, stroke, stable or unstable angina, peripheral artery disease, transient ischemic attack, or coronary or other arterial revascularization.
  • People 21 and older who have a very high level of bad cholesterol (190 mg/dL or higher).
  • People with Type 1 or Type 2 diabetes who are 40 to 75 years old.