施一弓前不久发了一篇老年痴呆γ分泌酶复合物结构的文章,能重复吗?
-
清华揭示老年痴呆症致病蛋白结构_新浪新闻 - 新浪新闻中心
做结构研究,最难的不是测试计算,而是拿到合适的样品。他的文章说:
We concluded that the human γ-secretase was in an active conformation. Nevertheless, there is a possibility that, given sample manipulation, the electron-microscopy structure described below may not represent the fully active conformation.
http://www.nature.com/nature/journal/v512/n7513/full/nature13567.html -
-