一个关键的实验

Drawing of an experiment that directly demonstrates that DNA is rearranged during B cell development.


Drawing of an experiment that directly demonstrates that DNA is rearranged during B cell development

The B cell tumor arose from a single B cell and therefore makes a single species of antibody molecule. The two radioactive DNA probes used are specific for the DNA sequences encoding the C region and the V region of the light chain that the tumor cells make.