老算法叫Friedewald method

The Friedewald method estimates LDL cholesterol using the following formula: total cholesterol minus high-density lipoprotein (HDL)—or “good” cholesterol—minus triglycerides divided by 5. That equation, the researchers say, applies a one-size-fits-all factor of 5 to everyone and doesn’t take into account variations among individuals. With the same information required for calculation as the Friedewald method, the newer method uses a chart developed by Johns Hopkins physicians with 180 different factors to more accurately calculate LDL cholesterol and individualize a person’s assessment. This equation is as follows: total cholesterol minus HDL cholesterol minus triglycerides divided by a specific value from the chart. The new test doesn’t take any longer to provide results to physicians and patients, and the cost is the same to administer.

 

有些lab的报告上面会注明是用新算法
最准的是直接测出来的LDL，但是费用高

https://www.hopkinsmedicine.org/news/newsroom/news-releases/new-cholesterol-calculation-may-avoid-need-to-fast-before-testing-study-suggests