回复：eb1-A换工作问题请教。

本人生物博士后，self-sponsor 申请 eb1-A 。材料几乎完全准备好以后突然因为某种原因换了实验室，所从事的领域与原来的稍有差异。 请问这对申请有影响吗？
-If it is just the research project/direction difference (e.g. liver disease to lung disease or skin disease), it should be fine because you still work in the same area (biomedical).

是否应该修改原材料还是按原样递上就可以？
-Up to you.