看看大城市的情况。。。。

Based on the latest available data through early 2026, Baltimore and San Francisco have the highest fatal drug overdose rates among large U.S. city/county jurisdictions. Data indicates a significant surge in fentanyl-related deaths in these areas. 

San Francisco Chronicle +3

The following list highlights cities and city-county jurisdictions with the highest overdose death rates, with data for 2024–2025 showing high mortality, particularly in the Mid-Atlantic and Pacific regions. 

 

Top U.S. Cities/Counties with Highest Drug Death Rates (2025–2026)

1. Baltimore, MD: Holds the highest drug overdose death rate, with nearly 
   

    
    deaths per 
   
   
   
    residents during the 12-month period ending in August 2025.
2. San Francisco, CA: Ranked second among large jurisdictions, with a rate of 
   

    
    per 
   
   
   
    residents in the same period.
3. Philadelphia, PA: Consistently ranks among the top cities for opioid-related deaths, with rates elevated by the crisis in neighborhoods like Kensington.
4. Washington, D.C.: Shows a high per capita overdose death rate, often ranking just below state-level leaders.
5. Cleveland, OH (Cuyahoga County): Ohio consistently ranks high in fentanyl-related mortality.
6. Cincinnati, OH (Hamilton County): A previous epicenter for carfentanil-related deaths, it maintains a high fatal overdose rate.
7. Dayton, OH: Has consistently experienced high overdose mortality rates due to the opioid crisis in Ohio.
8. Portland, OR: Has experienced a massive rise in overdose rates in recent years, placing it high among cities.
9. Seattle, WA (King County): Has experienced high fatality rates, often related to synthetic opioid use.
10. Indianapolis, IN (Marion County): Has reported drug intoxication as a leading cause of death, outranking car crashes and homicides. 
    San Francisco Chronicle +7

 

Key Data Trends & Context

• Most Dangerous Drug Threats: Fentanyl and methamphetamine dominate current overdose mortality rates.
• Recent Changes: While San Francisco and Baltimore have high rates, some data from early 2026 suggests total overdose deaths nationwide may be beginning to decline.
• Location Trends: The highest concentrations of overdose deaths are in the Northeast, Mid-Atlantic, and Ohio Valley