If you leave LA earlier in the first day, you may stop at Santa Barbara for 1.5 hours. Don't suggest you to visit Hearst castle since it's too tight. From Santa Barbara via 101-CA 1 to Carmel-By-Sea/Monterey it's 5.5 hours drive. You can stop at Big Sur (remember several vista points).
The CA-1 from Hearst Castle to big sur is a little difficult, some place speed limit is 15 miles only.
Do a little of home work to see the place worth to stop.
http://www.bigsurcalifornia.org/map.html
Stay night in Carmel or Monterey.
The second day you dirve from Monterey via CA-1 to Santa Cruz, then via HW 17-280 to Stanford. The next Nights in San Francisco.
The CA-1 from Hearst Castle to big sur is a little difficult, some place speed limit is 15 miles only.
Do a little of home work to see the place worth to stop.
http://www.bigsurcalifornia.org/map.html
Stay night in Carmel or Monterey.
The second day you dirve from Monterey via CA-1 to Santa Cruz, then via HW 17-280 to Stanford. The next Nights in San Francisco.