嘿嘿，你太不把自己当根葱了。Protocol 就是SOP，是楼上所说的GLP的基础。绝对的不是鸡毛蒜皮。以你

贴中的例子：What kind of risk would you take in your work?

对我来说，有两种风险，一种不可取，一种可取。后一种需要具备三个条件：1）必须性，2）成功性 3）性价比。

比如，我们曾有过一个样品量不够的问题，用了50盘材料都不够。解决方法有二。扩大样品量，用100盘，或更新程序。更新程序风险比较大，涉及到用新技术和投入大量时间和人力。作为实验室主管和高级科学家，我做出了更新程序的决定。经过反复调试，我们采用微米/纳米的技术，成功地更新了程序。新程序精简了整个工作过程，只用一半的时间，而且减少了25倍的人工和用材。

 

To me, there are two kinds of risks, one kind is worth taking, and the other one, not.  The ones that are worth taking have 3 conditions: 1) necessity, 2) the probability of success and 3) the ratio of cost and reward.

For example, we had a problem of not getting enough samples, even from 50 plates.  We could enlarge the sample pool by having 100 plates, or we could change the protocol to reduce the volumes of sample usage. The later was more risky, it requires advanced technology and we had to spend quite a lot of time to develop a new protocol. As the lab manager and senior scientist, I made the dicision to take the risk. After quite a bit trial and error and vigorously  brain storm.  We successfully developed a new protocol using micro/nano technology.  The new protocol streamlined whole process, cut time by half, reduce labor and materials by 25 times.