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本人持有B2十年签证，我想在境内转F1，请问有可操作性吗？

-Yes, but if you have got the I-20 from a school, you had better apply for the F-1 visa to enter US.

要申请的话是否入境就开始申请？

-At least 3 months, in case USCIS think you have made a decision to study in US before you enter US using B-2 visa(this is visa fraud).

有知道具体怎么办的吗？谢谢！

-File I-530. Talk to the school and they will help you. By the way, B-2 to F-1 normally may take more than 6 months to be approved. So, it is better to use F-1 visa to enter US.