谢谢，懂医学特别是疫苗能否给解释一下这个结论是什么意思？其中mRNA接种量远远大于其它疫苗，可否给重点诠释一下？

Conclusion

Observed vs. expected analyses in a multi-country context of the GVDN and the GCoVS Project offers a larger and more diverse dataset, enhanced generalizability, and improved statistical power over single site or regional studies. It also presents challenges related to data heterogeneity, population confounding factors, and variations in vaccination strategies and reporting systems. The involvement of researchers and data sources from diverse regions of the world promotes inclusivity, reduces potential biases, and fosters collaboration in the pursuit of a shared public health goal. While our study confirmed previously identified rare safety signals following COVID-19 vaccination and contributed evidence on several other important outcomes, further investigation is warranted to confirm associations and assess clinical significance. This could be addressed by conducting association studies specific to individual outcomes by applying methodologies such as the self-controlled case series (SCCS) to validate the associations