孩子有自闭症的问题，40岁以上产妇，与25-29年龄段产妇相比，风险

孩子有自闭症的问题，40岁以上产妇，与25-29年龄段产妇相比，风险增加51%；与25岁以下产妇相比，风险增加77%。据此换算，如果40岁以上产妇孩子有自闭症的风险为100，那么：

产妇年龄段      相对风险

<25                   56.5

25-29                66.2

>40                  100

另外，有文献指出，高龄产妇生下的女孩，偏男性化。

信息来源：

Study Confirms Link between Older Maternal Age and Autism，Maternal age and autism are both on the rise--but only a small fraction of the increasing incidence can be explained by the trend toward later childbearing

https://www.scientificamerican.com/article/autism-maternal-age/

The researchers found that mothers over 40 had a 51 percent higher risk of having a child with autism than mothers 25 to 29, and a 77 percent higher risk than mothers under 25. Autism—a developmental disorder characterized by impaired social interaction and communication—appears to be on the rise.