排除无脑儿,脊柱裂有不同亚型,预后好坏和原发defect严重程度有关。这篇NIH的文献应该有帮助。

来源: 志在千里 2016-11-11 15:38:42 [] [旧帖] [给我悄悄话] 本文已被阅读: 次 (2772 bytes)

如果不是无脑儿,脊柱裂有不同亚型,治疗方法, 预后好坏和原发defect严重程度有关。这篇NIH的文献应该有帮助。在国内检查,接生,治疗都应该找三甲医院.

http://www.ninds.nih.gov/disorders/spina_bifida/detail_spina_bifida.htm

What is spina bifida?

 

Spina bifida, which literally means “cleft spine,” is characterized by the incomplete development of the brain, spinal cord, and/or meninges (the protective covering around the brain and spinal cord).   It is the most common neural tube defect in the United States—affecting 1,500 to 2,000 of the more than 4 million babies born in the country each year. An estimated 166,000 individuals with spina bifida live in the United States.

 

What are the different types of spina bifida?

 

There are four types of spina bifida:  occulta, closed neural tube defects, meningocele, and myelomeningocele.

Occulta is the mildest and most common form in which one or more vertebrae are malformed.  The name “occulta,” which means “hidden,” indicates that a layer of skin covers the malformation, or opening in the vertebrae.  This form of spina bifida, present in 10-20 percent of the general population, rarely causes disability or symptoms.

Closed neural tube defects make up the second type of spina bifida.  This form consists of a diverse group of defects in which the spinal cord is marked by malformations of fat, bone, or meninges.  In most instances there are few or no symptoms; in others the malformation causes incomplete paralysis with urinary and bowel dysfunction.

In the third type, meningocele, spinal fluid and meninges protrude through an abnormal vertebral opening; the malformation contains no neural elements and may or may not be covered by a layer of skin.   Some individuals with meningocele may have few or no symptoms while others may experience such symptoms as complete paralysis with bladder and bowel dysfunction.

Myelomeningocele, the fourth form, is the most severe and occurs when the spinal cord/neural elements are exposed through the opening in the spine, resulting in partial or complete paralysis of the parts of the body below the spinal opening.  The impairment may be so severe that the affected individual is unable to walk and may have bladder and bowel dysfunction. 

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